Computational approach to discriminate human and mouse sequences in patient-derived tumour xenografts

BACKGROUND: Patient-Derived Tumour Xenografts (PDTXs) have emerged as the pre-clinical models that best represent clinical tumour diversity and intra-tumour heterogeneity. The molecular characterization of PDTXs using High-Throughput Sequencing (HTS) is essential; however, the presence of mouse stro...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Callari, Maurizio, Batra, Ankita Sati, Batra, Rajbir Nath, Sammut, Stephen-John, Greenwood, Wendy, Clifford, Harry, Hercus, Colin, Chin, Suet-Feung, Bruna, Alejandra, Rueda, Oscar M., Caldas, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5755132/
https://ncbi.nlm.nih.gov/pubmed/29304755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-4414-y
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