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Computational approach to discriminate human and mouse sequences in patient-derived tumour xenografts
BACKGROUND: Patient-Derived Tumour Xenografts (PDTXs) have emerged as the pre-clinical models that best represent clinical tumour diversity and intra-tumour heterogeneity. The molecular characterization of PDTXs using High-Throughput Sequencing (HTS) is essential; however, the presence of mouse stro...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | BMC Genomics |
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| Κύριοι συγγραφείς: | , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BioMed Central
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5755132/ https://ncbi.nlm.nih.gov/pubmed/29304755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-4414-y |
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