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Functional genomics analyses of RNA-binding proteins reveal the splicing regulator SNRPB as an oncogenic candidate in glioblastoma

BACKGROUND: Glioblastoma (GBM) is the most common and aggressive type of brain tumor. Currently, GBM has an extremely poor outcome and there is no effective treatment. In this context, genomic and transcriptomic analyses have become important tools to identify new avenues for therapies. RNA-binding...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Correa, Bruna R., de Araujo, Patricia Rosa, Qiao, Mei, Burns, Suzanne C., Chen, Chen, Schlegel, Richard, Agarwal, Seema, Galante, Pedro A. F., Penalva, Luiz O. F.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4901439/
https://ncbi.nlm.nih.gov/pubmed/27287018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0990-4
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