Genomic analyses of early responses to radiation inglioblastoma reveal new alterations at transcription,splicing, and translation levels

High-dose radiation is the main component of glioblastoma therapy. Unfortunately, radio-resistance is a common problem and a major contributor to tumor relapse. Understanding the molecular mechanisms driving response to radiation is critical for identifying regulatory routes that could be targeted t...

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Publicado en:Sci Rep
Autores principales: Choudhary, Saket, Burns, Suzanne C., Mirsafian, Hoda, Li, Wenzheng, Vo, Dat T., Qiao, Mei, Lei, Xiufen, Smith, Andrew D., Penalva, Luiz O.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7265345/
https://ncbi.nlm.nih.gov/pubmed/32488114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65638-1
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