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Enhanced conformational sampling to visualize a free-energy landscape of protein complex formation

We introduce various, recently developed, generalized ensemble methods, which are useful to sample various molecular configurations emerging in the process of protein–protein or protein–ligand binding. The methods introduced here are those that have been or will be applied to biomolecular binding, w...

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Vydáno v:Biochem J
Hlavní autoři: Iida, Shinji, Nakamura, Haruki, Higo, Junichi
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4901360/
https://ncbi.nlm.nih.gov/pubmed/27288028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20160053
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