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Enhanced conformational sampling to visualize a free-energy landscape of protein complex formation

We introduce various, recently developed, generalized ensemble methods, which are useful to sample various molecular configurations emerging in the process of protein–protein or protein–ligand binding. The methods introduced here are those that have been or will be applied to biomolecular binding, w...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Iida, Shinji, Nakamura, Haruki, Higo, Junichi
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4901360/
https://ncbi.nlm.nih.gov/pubmed/27288028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20160053
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