Interferon-γ–Induced Unfolded Protein Response in Conjunctival Goblet Cells as a Cause of Mucin Deficiency in Sjögren Syndrome

Goblet cells (GCs) are specialized secretory cells that produce mucins and a variety of other proteins. Significant conjunctival GC loss occurs in both experimental dry eye models and patients with keratoconjunctivitis sicca due to the induction of interferon (IFN)-γ. With the use of a primary murin...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Coursey, Terry G., Tukler Henriksson, Johanna, Barbosa, Flavia L., de Paiva, Cintia S., Pflugfelder, Stephen C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2016
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4901135/
https://ncbi.nlm.nih.gov/pubmed/27085137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.02.004
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados