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Topical Interferon-gamma Neutralization Prevents Conjunctival Goblet Cell Loss in Experimental Murine Dry Eye

Evidence suggests that the cytokine interferon (IFN)-γ released by natural killer and CD4+ T cells contributes to the conjunctival goblet cell (GC) loss in dry eye. The purpose of this study was to investigate if topical neutralization of IFN-γ prevents or alleviates GC loss in an experimental desic...

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Detalhes bibliográficos
Main Authors: Zhang, Xiaobo, De Paiva, Cintia S., Su, Zhitao, Volpe, Eugene A., Li, De-Quan, Pflugfelder, Stephen C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901360/
https://ncbi.nlm.nih.gov/pubmed/24315969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2013.11.011
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