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Interferon-gamma deficiency protects against aging-related goblet cell loss

Aging is a well-recognized risk factor for dry eye. Interferon-gamma (IFN-γ) has been implicated in conjunctival keratinization and goblet cell loss in dry eye. We investigated the role of IFN-γ in age-related dry eye by evaluating young (8 weeks) and aged (15 months; 15M) C57BL/6 (B6) and IFN-γKO m...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Volpe, Eugene A., Henriksson, Johanna Tukler, Wang, Changjun, Barbosa, Flavia L., Zaheer, Mahira, Zhang, Xiaobo, Pflugfelder, Stephen C., de Paiva, Cintia S.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323102/
https://ncbi.nlm.nih.gov/pubmed/27623073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11872
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