Interferon-γ–Induced Unfolded Protein Response in Conjunctival Goblet Cells as a Cause of Mucin Deficiency in Sjögren Syndrome

Goblet cells (GCs) are specialized secretory cells that produce mucins and a variety of other proteins. Significant conjunctival GC loss occurs in both experimental dry eye models and patients with keratoconjunctivitis sicca due to the induction of interferon (IFN)-γ. With the use of a primary murin...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Am J Pathol
Glavni autori: Coursey, Terry G., Tukler Henriksson, Johanna, Barbosa, Flavia L., de Paiva, Cintia S., Pflugfelder, Stephen C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2016
Teme:
Regular Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4901135/
https://ncbi.nlm.nih.gov/pubmed/27085137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.02.004
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items