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Membrane Tension Acts Through PLD2 and mTORC2 to Limit Actin Network Assembly During Neutrophil Migration

For efficient polarity and migration, cells need to regulate the magnitude and spatial distribution of actin assembly. This process is coordinated by reciprocal interactions between the actin cytoskeleton and mechanical forces. Actin polymerization-based protrusion increases tension in the plasma me...

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Pubblicato in:PLoS Biol
Autori principali: Diz-Muñoz, Alba, Thurley, Kevin, Chintamen, Sana, Altschuler, Steven J., Wu, Lani F., Fletcher, Daniel A., Weiner, Orion D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900667/
https://ncbi.nlm.nih.gov/pubmed/27280401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002474
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