Protein Kinase D and Gβγ Subunits Mediate Agonist-evoked Translocation of Protease-activated Receptor-2 from the Golgi Apparatus to the Plasma Membrane

Agonist-evoked endocytosis of G protein-coupled receptors has been extensively studied. The mechanisms by which agonists stimulate mobilization and plasma membrane translocation of G protein-coupled receptors from intracellular stores are unexplored. Protease-activated receptor-2 (PAR(2)) traffics t...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Jensen, Dane D., Zhao, Peishen, Jimenez-Vargas, Nestor N., Lieu, TinaMarie, Gerges, Marina, Yeatman, Holly R., Canals, Meritxell, Vanner, Stephen J., Poole, Daniel P., Bunnett, Nigel W.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2016
Sujets:
Signal Transduction
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900274/
https://ncbi.nlm.nih.gov/pubmed/27030010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.710681
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