טוען...
Crystal structure of Cpf1 in complex with guide RNA and target DNA
Cpf1 is an RNA-guided endonuclease of a type V CRISPR-Cas system that has been recently harnessed for genome editing. Here, we report the crystal structure of Acidaminococcus sp. Cpf1 (AsCpf1) in complex with the guide RNA and its target DNA, at 2.8 Å resolution. AsCpf1 adopts a bilobed architecture...
שמור ב:
| הוצא לאור ב: | Cell |
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| Main Authors: | , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4899970/ https://ncbi.nlm.nih.gov/pubmed/27114038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.04.003 |
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