PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells

Both positive and negative regulatory roles have been suggested for the B7 family member PD-L1(B7-H1). PD-L1 is expressed on antigen-presenting cells (APCs), activated T cells, and a variety of tissues, but the functional significance of PD-L1 on each cell type is not yet clear. To dissect the funct...

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Detaylı Bibliyografya
Asıl Yazarlar: Latchman, Yvette E., Liang, Spencer C., Wu, Yin, Chernova, Tatyana, Sobel, Raymond A., Klemm, Martina, Kuchroo, Vijay K., Freeman, Gordon J., Sharpe, Arlene H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2004
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC489996/
https://ncbi.nlm.nih.gov/pubmed/15249675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307252101
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