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Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis
Age is a significant risk factor for the development of cancer. However, the mechanisms that drive age-related increases in cancer remain poorly understood. To determine if senescent stromal cells influence tumorigenesis, we develop a mouse model that mimics the aged skin microenvironment. Using thi...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4899869/ https://ncbi.nlm.nih.gov/pubmed/27272654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11762 |
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