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Inhibition of herpes simplex virus 1 gene expression and replication by RNase P-associated external guide sequences

An external guide sequence (EGS) is a RNA sequence which can interact with a target mRNA to form a tertiary structure like a pre-tRNA and recruit intracellular ribonuclease P (RNase P), a tRNA processing enzyme, to degrade target mRNA. Previously, an in vitro selection procedure has been used by us...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Liu, Jin, Shao, Luyao, Trang, Phong, Yang, Zhu, Reeves, Michael, Sun, Xu, Vu, Gia-Phong, Wang, Yu, Li, Hongjian, Zheng, Congyi, Lu, Sangwei, Liu, Fenyong
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899697/
https://ncbi.nlm.nih.gov/pubmed/27279482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27068
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