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Ribonuclease P-mediated inhibition of human cytomegalovirus gene expression and replication induced by engineered external guide sequences

External guide sequences (EGSs) are RNA molecules that can bind to a target mRNA and direct ribonuclease P (RNase P), a tRNA processing enzyme, for specific cleavage of the target mRNA. Using an in vitro selection procedure, we have previously generated EGS variants that efficiently direct human RNa...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jiang, Xiaohong, Chen, Yuan-Chuan, Gong, Hao, Trang, Phong, Lu, Sangwei, Liu, Fenyong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579886/
https://ncbi.nlm.nih.gov/pubmed/23018778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.21724
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