Inhibition of human cytomegalovirus major capsid protein expression and replication by ribonuclease P–associated external guide sequences

External guide sequences (EGSs) signify the short RNAs that induce ribonuclease P (RNase P), an enzyme responsible for processing the 5′ termini of tRNA, to specifically cleave a target mRNA by forming a precursor tRNA-like complex. Hence, the EGS technology may serve as a potential strategy for gen...

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Pubblicato in:RNA
Autori principali: Deng, Qiudi, Liu, Yujun, Li, Xin, Yan, Bin, Sun, Xu, Tang, Wei, Trang, Phong, Yang, Zhu, Gong, Hao, Wang, Yu, Lu, Jie, Chen, Jun, Xia, Chuan, Xing, Xiwen, Lu, Sangwei, Liu, Fenyong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467005/
https://ncbi.nlm.nih.gov/pubmed/30803999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.069682.118
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