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Integrative structural biology of Tetrahymena telomerase: insights into catalytic mechanism and interaction at telomeres

Telomerase is a ribonucleoprotein complex that helps maintain telomeres, the physical ends of linear chromosomes. The low cellular levels of telomerase, propensity for TERT and other telomerase proteins to aggregate, and cell cycle regulation of telomerase assembly in most organisms has made it a ch...

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Dettagli Bibliografici
Pubblicato in:FEBS J
Autori principali: Feigon, Juli, Chan, Henry, Jiang, Jiansen
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899323/
https://ncbi.nlm.nih.gov/pubmed/26918633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13691
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