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A structurally conserved human and Tetrahymena telomerase catalytic core

Telomerase is a ribonucleoprotein complex that counteracts the shortening of chromosome ends due to incomplete replication. Telomerase contains a catalytic core of telomerase reverse transcriptase (TERT) and telomerase RNA (TER). However, what defines TERT and separates it from other reverse transcr...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wang, Yaqiang, Gallagher-Jones, Marcus, Sušac, Lukas, Song, He, Feigon, Juli
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733840/
https://ncbi.nlm.nih.gov/pubmed/33229538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2011684117
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