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Structurally conserved five nucleotide bulge determines the overall topology of the core domain of human telomerase RNA

Telomerase is a unique ribonucleoprotein complex that catalyzes the addition of telomeric DNA repeats onto the 3′ ends of linear chromosomes. All vertebrate telomerase RNAs contain a catalytically essential core domain that includes the template and a pseudoknot with extended helical subdomains. Wit...

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Detalhes bibliográficos
Main Authors: Zhang, Qi, Kim, Nak-Kyoon, Peterson, Robert D., Wang, Zhonghua, Feigon, Juli
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2973926/
https://ncbi.nlm.nih.gov/pubmed/20966348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013269107
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