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Structure and sequence elements of the CR4/5 domain of medaka telomerase RNA important for telomerase function

Telomerase is a unique reverse transcriptase that maintains the 3′ ends of eukaryotic chromosomes by adding tandem telomeric repeats. The RNA subunit (TR) of vertebrate telomerase provides a template for reverse transcription, contained within the conserved template/pseudoknot domain, and a conserve...

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Bibliographic Details
Main Authors: Kim, Nak-Kyoon, Zhang, Qi, Feigon, Juli
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950677/
https://ncbi.nlm.nih.gov/pubmed/24335084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1276
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