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Integrative structural biology of Tetrahymena telomerase: insights into catalytic mechanism and interaction at telomeres

Telomerase is a ribonucleoprotein complex that helps maintain telomeres, the physical ends of linear chromosomes. The low cellular levels of telomerase, propensity for TERT and other telomerase proteins to aggregate, and cell cycle regulation of telomerase assembly in most organisms has made it a ch...

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Detalhes bibliográficos
Publicado no:FEBS J
Main Authors: Feigon, Juli, Chan, Henry, Jiang, Jiansen
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899323/
https://ncbi.nlm.nih.gov/pubmed/26918633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13691
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