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Integrative structural biology of Tetrahymena telomerase: insights into catalytic mechanism and interaction at telomeres

Telomerase is a ribonucleoprotein complex that helps maintain telomeres, the physical ends of linear chromosomes. The low cellular levels of telomerase, propensity for TERT and other telomerase proteins to aggregate, and cell cycle regulation of telomerase assembly in most organisms has made it a ch...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:FEBS J
Main Authors: Feigon, Juli, Chan, Henry, Jiang, Jiansen
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899323/
https://ncbi.nlm.nih.gov/pubmed/26918633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13691
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