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MTHFD1 Regulates Nuclear de novo Thymidylate Biosynthesis and Genome Stability

Disruptions in folate-mediated one-carbon metabolism (FOCM) are associated with risk for several pathologies including developmental anomalies such as neural tube defects and congenital heart defects, diseases of aging including cognitive decline, neurodegeneration and epithelial cancers, and hemato...

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Bibliografiska uppgifter
I publikationen:Biochimie
Huvudupphovsmän: Field, Martha S., Kamynina, Elena, Stover, Patrick J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899284/
https://ncbi.nlm.nih.gov/pubmed/26853819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2016.02.001
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