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CD5-mediated inhibition of TCR signaling proceeds normally in the absence of SHP-1
The CD5 transmembrane glycoprotein functions as a co-receptor in the signaling pathway linking T-cell antigen receptor (TCR) engagement to activation and differentiation. Although CD5 effects on TCR signaling have been shown to be primarily inhibitory, the underlying mechanisms remain unclear. In vi...
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| Pubblicato in: | Int J Mol Med |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
D.A. Spandidos
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4899029/ https://ncbi.nlm.nih.gov/pubmed/27221212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2016.2592 |
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