Surface expression of the beta T cell receptor (TCR) chain in the absence of other TCR or CD3 proteins on immature T cells.

T cell receptor (TCR) beta genes are rearranged prior to TCR alpha genes. A productively rearranged TCR beta gene suppresses further V beta gene rearrangement. Here we show that in beta TCR transgenic mice the TCR beta-chain can be expressed on the surface of immature CD4-8- thymocytes, but not on m...

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Detalles Bibliográficos
Publicado en:EMBO J
Main Authors: Kishi, H, Borgulya, P, Scott, B, Karjalainen, K, Traunecker, A, Kaufman, J, von Boehmer, H
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1991
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452616/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1703490/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb07924.x
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