Surface expression of the beta T cell receptor (TCR) chain in the absence of other TCR or CD3 proteins on immature T cells.

T cell receptor (TCR) beta genes are rearranged prior to TCR alpha genes. A productively rearranged TCR beta gene suppresses further V beta gene rearrangement. Here we show that in beta TCR transgenic mice the TCR beta-chain can be expressed on the surface of immature CD4-8- thymocytes, but not on m...

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Bibliographic Details
Main Authors: Kishi, H, Borgulya, P, Scott, B, Karjalainen, K, Traunecker, A, Kaufman, J, von Boehmer, H
Format: Artigo
Language:Inglês
Published: 1991
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC452616/
https://ncbi.nlm.nih.gov/pubmed/1703490
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