Development of the CD4 and CD8 lineage of T cells: instruction versus selection.

T cells bearing the alpha beta T cell receptor (TCR) can be divided into CD4+8- and CD4-8+ subsets which develop in the thymus from CD4+8+ precursors. The commitment to the CD4 and CD8 lineage depends on the binding of the alpha beta TCR to thymic major histocompatibility complex (MHC) coded class I...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Borgulya, P, Kishi, H, Müller, U, Kirberg, J, von Boehmer, H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC452734/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1901264/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1991.tb08024.x
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