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Autoimmune diseases — connecting risk alleles with molecular traits of the immune system

Genome-wide strategies have driven the discovery of more than 300 susceptibility loci for autoimmune diseases. However, for almost all loci, understanding of the mechanisms leading to autoimmunity remains limited, and most variants that are likely to be causal are in non-coding regions of the genome...

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Dades bibliogràfiques
Publicat a:Nat Rev Genet
Autors principals: Gutierrez-Arcelus, Maria, Rich, Stephen S., Raychaudhuri, Soumya
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896831/
https://ncbi.nlm.nih.gov/pubmed/26907721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg.2015.33
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