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Autoimmune diseases — connecting risk alleles with molecular traits of the immune system
Genome-wide strategies have driven the discovery of more than 300 susceptibility loci for autoimmune diseases. However, for almost all loci, understanding of the mechanisms leading to autoimmunity remains limited, and most variants that are likely to be causal are in non-coding regions of the genome...
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| Pubblicato in: | Nat Rev Genet |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4896831/ https://ncbi.nlm.nih.gov/pubmed/26907721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg.2015.33 |
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