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A binding site outside the canonical PDZ domain determines the specific interaction between Shank and SAPAP and their function

Shank and SAPAP (synapse-associated protein 90/postsynaptic density-95–associated protein) are two highly abundant scaffold proteins that directly interact with each other to regulate excitatory synapse development and plasticity. Mutations of SAPAP, but not other reported Shank PDZ domain binders,...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Zeng, Menglong, Shang, Yuan, Guo, Tingfeng, He, Qinghai, Yung, Wing-Ho, Liu, Kai, Zhang, Mingjie
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896714/
https://ncbi.nlm.nih.gov/pubmed/27185935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1523265113
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