A binding site outside the canonical PDZ domain determines the specific interaction between Shank and SAPAP and their function

Shank and SAPAP (synapse-associated protein 90/postsynaptic density-95–associated protein) are two highly abundant scaffold proteins that directly interact with each other to regulate excitatory synapse development and plasticity. Mutations of SAPAP, but not other reported Shank PDZ domain binders,...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Zeng, Menglong, Shang, Yuan, Guo, Tingfeng, He, Qinghai, Yung, Wing-Ho, Liu, Kai, Zhang, Mingjie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2016
Konular:
PNAS Plus
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896714/
https://ncbi.nlm.nih.gov/pubmed/27185935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1523265113
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