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Domain-swapped dimerization of ZO-1 PDZ2 generates specific and regulatory connexin43-binding sites

PDZ domain scaffold proteins are capable of assembling macromolecular protein complexes in diverse cellular processes through PDZ-mediated binding to a short peptide fragment at the carboxyl tail of target proteins. How each PDZ domain specifically recognizes its target protein(s) remains a major co...

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Détails bibliographiques
Auteurs principaux: Chen, Jia, Pan, Lifeng, Wei, Zhiyi, Zhao, Yanxiang, Zhang, Mingjie
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516886/
https://ncbi.nlm.nih.gov/pubmed/18636092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.138
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