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Domain Swapping within PDZ2 Is Responsible for Dimerization of ZO Proteins

ZO-1 is a multidomain protein involved in cell-cell junctions and contains three PDZ domains, which are necessary for its function in vivo. PDZ domains play a central role in assembling diverse protein complexes through their ability to recognize short peptide motifs on other proteins. We determined...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fanning, Alan S., Lye, Ming F., Anderson, James M., Lavie, Arnon
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661428/
https://ncbi.nlm.nih.gov/pubmed/17928286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M707255200
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