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Coronavirus receptor switch explained from the stereochemistry of protein–carbohydrate interactions and a single mutation
Hemagglutinin-esterases (HEs) are bimodular envelope proteins of orthomyxoviruses, toroviruses, and coronaviruses with a carbohydrate-binding “lectin” domain appended to a receptor-destroying sialate-O-acetylesterase (“esterase”). In concert, these domains facilitate dynamic virion attachment to cel...
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| Опубликовано в: : | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4896708/ https://ncbi.nlm.nih.gov/pubmed/27185912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1519881113 |
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