D-Serine Is a Substrate for Neutral Amino Acid Transporters ASCT1/SLC1A4 and ASCT2/SLC1A5, and Is Transported by Both Subtypes in Rat Hippocampal Astrocyte Cultures

N-methyl-D-aspartate (NMDA) receptors play critical roles in synaptic transmission and plasticity. Activation of NMDA receptors by synaptically released L-glutamate also requires occupancy of co-agonist binding sites in the tetrameric receptor by either glycine or D-serine. Although D-serine appears...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Foster, Alan C., Farnsworth, Jill, Lind, Genevieve E., Li, Yong-Xin, Yang, Jia-Ying, Dang, Van, Penjwini, Mahmud, Viswanath, Veena, Staubli, Ursula, Kavanaugh, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896441/
https://ncbi.nlm.nih.gov/pubmed/27272177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156551
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