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Fast, accurate, and lightweight analysis of BS-treated reads with ERNE 2

BACKGROUND: Bisulfite treatment of DNA followed by sequencing (BS-seq) has become a standard technique in epigenetic studies, providing researchers with tools for generating single-base resolution maps of whole methylomes. Aligning bisulfite-treated reads, however, is a computationally difficult tas...

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Bibliographic Details
Published in:BMC Bioinformatics
Main Authors: Prezza, Nicola, Vezzi, Francesco, Käller, Max, Policriti, Alberto
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896272/
https://ncbi.nlm.nih.gov/pubmed/26961371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-0910-3
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