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Fast and accurate long-read assembly with wtdbg2

Existing long-read assemblers require thousands of CPU hours to assemble a human genome and are being outpaced by sequencing technologies in terms of both throughput and cost. We developed a long-read assembler wtdbg2 (https://github.com/ruanjue/wtdbg2) that is 2–17 times as fast as published tools...

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Détails bibliographiques
Publié dans:Nat Methods
Auteurs principaux: Ruan, Jue, Li, Heng
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004874/
https://ncbi.nlm.nih.gov/pubmed/31819265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-019-0669-3
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