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Fast and accurate long-read alignment with Burrows–Wheeler transform

Motivation: Many programs for aligning short sequencing reads to a reference genome have been developed in the last 2 years. Most of them are very efficient for short reads but inefficient or not applicable for reads >200 bp because the algorithms are heavily and specifically tuned for short quer...

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Dettagli Bibliografici
Autori principali: Li, Heng, Durbin, Richard
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828108/
https://ncbi.nlm.nih.gov/pubmed/20080505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp698
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