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MICOS and phospholipid transfer by Ups2–Mdm35 organize membrane lipid synthesis in mitochondria

Mitochondria exert critical functions in cellular lipid metabolism and promote the synthesis of major constituents of cellular membranes, such as phosphatidylethanolamine (PE) and phosphatidylcholine. Here, we demonstrate that the phosphatidylserine decarboxylase Psd1, located in the inner mitochond...

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Bibliografske podrobnosti
izdano v:J Cell Biol
Main Authors: Aaltonen, Mari J., Friedman, Jonathan R., Osman, Christof, Salin, Bénédicte, di Rago, Jean-Paul, Nunnari, Jodi, Langer, Thomas, Tatsuta, Takashi
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896057/
https://ncbi.nlm.nih.gov/pubmed/27241913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201602007
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