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Regulation of mitochondrial phospholipids by Ups1/PRELI-like proteins depends on proteolysis and Mdm35

The mitochondrial phospholipid metabolism critically depends on members of the conserved Ups1/PRELI-like protein family in the intermembrane space. Ups1 and Ups2 (also termed Gep1) were shown to regulate the accumulation of cardiolipin (CL) and phosphatidylethanolamine (PE), respectively, in a lipid...

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Detalhes bibliográficos
Main Authors: Potting, Christoph, Wilmes, Claudia, Engmann, Tanja, Osman, Christof, Langer, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944050/
https://ncbi.nlm.nih.gov/pubmed/20657548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.169
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