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Quality control of mitochondria: protection against neurodegeneration and ageing

Dysfunction of mitochondria has severe cellular consequences and is linked to ageing and neurodegeneration in human. Several surveillance strategies have evolved that limit mitochondrial damage and ensure cellular integrity. Intraorganellar proteases conduct protein quality control and exert regulat...

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Detalhes bibliográficos
Main Authors: Tatsuta, Takashi, Langer, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234350/
https://ncbi.nlm.nih.gov/pubmed/18216873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601972
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