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Structure of the intact ATM/Tel1 kinase
The ataxia-telangiectasia mutated (ATM) protein is an apical kinase that orchestrates the multifaceted DNA-damage response. Normally, ATM kinase is in an inactive, homodimer form and is transformed into monomers upon activation. Besides a conserved kinase domain at the C terminus, ATM contains three...
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| I publikationen: | Nat Commun |
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| Huvudupphovsmän: | , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Nature Publishing Group
2016
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4894967/ https://ncbi.nlm.nih.gov/pubmed/27229179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11655 |
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