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The apelin receptor: Physiology, pathology, cell signalling, and ligand modulation of a peptide-activated class A GPCR

The apelin receptor (AR or APJ) is a class A (rhodopsin-like) G-protein coupled receptor (GPCR) with wide distribution throughout the human body. Activation of the AR by its cognate peptide ligand, apelin, induces diverse physiological effects including vasoconstriction and dilation; strengthening o...

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Bibliografske podrobnosti
izdano v:Biochem Cell Biol
Main Authors: Chapman, Nigel A., Dupré, Denis J., Rainey, Jan K.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894813/
https://ncbi.nlm.nih.gov/pubmed/25275559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1139/bcb-2014-0072
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