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Novel designer receptors to probe GPCR signaling and physiology
Muscarinic receptor-based designer receptors have as powerful novel tools to study G-proteincoupled receptor (GPCR) signaling and physiology. These new designer GPCRs, which are most frequently referred to as DREADDs (designer receptors exclusively activated by designer drug), are unable to bind ace...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3758874/ https://ncbi.nlm.nih.gov/pubmed/23769625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2013.04.006 |
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