Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake

Agouti-related peptide (AgRP) neurons of the hypothalamus play a key role in regulating food intake and body weight, by releasing three different orexigenic molecules: AgRP; GABA; and neuropeptide Y. AgRP neurons express various G protein-coupled receptors (GPCRs) with different coupling properties,...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Nakajima, Ken-ichiro, Cui, Zhenzhong, Li, Chia, Meister, Jaroslawna, Cui, Yinghong, Fu, Ou, Smith, Adam S., Jain, Shalini, Lowell, Bradford B., Krashes, Michael J., Wess, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729878/
https://ncbi.nlm.nih.gov/pubmed/26743492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10268
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