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Bioactivity of the putative apelin proprotein expands the repertoire of apelin receptor ligands
BACKGROUND: Apelin is a peptide ligand for a class A G-protein coupled receptor called the apelin receptor (AR or APJ) that regulates angiogenesis, the adipoinsular axis, and cardiovascular functions. Apelin has been shown to be bioactive as 13, 17, and 36 amino acid isoforms, C-terminal fragments o...
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| Publicado en: | Biochim Biophys Acta |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5770203/ https://ncbi.nlm.nih.gov/pubmed/28546009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2017.05.017 |
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