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Distinct domains of Complexin I differentially regulate neurotransmitter release

Complexins constitute a family of four synaptic high-affinity SNARE complex binding proteins. They positively regulate a late, post-priming step in Ca(2+)-triggered synchronous neurotransmitter release, but the underlying molecular mechanisms are unclear. We show here that SNARE complex binding of C...

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Pubblicato in:Nat Struct Mol Biol
Autori principali: Xue, Mingshan, Reim, Kerstin, Chen, Xiaocheng, Chao, Hsiao-Tuan, Deng, Hui, Rizo, Josep, Brose, Nils, Rosenmund, Christian
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894543/
https://ncbi.nlm.nih.gov/pubmed/17828276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1292
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