Sandwich-Cultured Hepatocytes as a Tool to Study Drug Disposition and Drug-Induced Liver Injury

Sandwich-cultured hepatocytes (SCH) are metabolically competent and have proper localization of basolateral and canalicular transporters with functional bile networks. Therefore, this cellular model is a unique tool that can be used to estimate biliary excretion of compounds. SCH have been used wide...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :J Pharm Sci
Главные авторы: YANG, KYUNGHEE, GUO, CEN, WOODHEAD, JEFFREY L, CLAIRE, ROBERT LST., WATKINS, PAUL B, SILER, SCOTT Q, HOWELL, BRETT A, BROUWER, KIM LR
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894499/
https://ncbi.nlm.nih.gov/pubmed/26869411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2015.11.008
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы