Development of a cell system for siRNA screening of pathogen responses in human and mouse macrophages

Macrophages play a critical role in the innate immune response to pathogen infection, but few tools exist for systematic dissection of these responses using modern genome-wide perturbation methods. To develop an assay platform for high-throughput analysis of macrophage activation by pathogenic stimu...

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Publicat a:Sci Rep
Autors principals: Li, Ning, Sun, Jing, Benet, Zachary L., Wang, Ze, Al-Khodor, Souhaila, John, Sinu P., Lin, Bin, Sung, Myong-Hee, Fraser, Iain D. C.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4894436/
https://ncbi.nlm.nih.gov/pubmed/25831078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09559
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