Repression of the antioxidant NRF2 pathway in premature aging

Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare, invariably fatal premature aging disorder. The disease is caused by constitutive production of progerin, a mutant form of the nuclear architectural protein lamin A, leading, through unknown mechanisms, to diverse morphological, epigenetic and ge...

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Bibliographic Details
Published in:	Cell
Main Authors:	Kubben, Nard, Zhang, Weiqi, Wang, Lixia, Voss, Ty C., Yang, Jiping, Qu, Jing, Liu, Guang-Hui, Misteli, Tom
Format:	Artigo
Language:	Inglês
Published:	2016
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4893198/ https://ncbi.nlm.nih.gov/pubmed/27259148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.05.017
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Repression of the antioxidant NRF2 pathway in premature aging

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